The Role of Glucoseamine Sulfate on Osteoarthritis: An update

Md Rashidul Hasan,Md Faizul Islam Chowdhury,M Matiur Rahman,HAM Nazmul Ahasan

doi:10.3329/jom.v7i1.1359

Abstract

DOI = 10.3329/jom.v7i1.1359 J MEDICINE 2006; 7 : 32-35

Highlights

Osteoarthritis, the most common form of arthritis is an age related degenerative disease of joint cartilage
In early stage of disease or injury, these factors may have a catabolic effect on the proteoglycans degradation and synthesis balance
Some research indicates that glucose amine may have little, if any, effect on severe cartilage injuries or advance diseases

Summary

Introduction

Osteoarthritis, the most common form of arthritis is an age related degenerative disease of joint cartilage. Patients in the glucoseamine group did not experience any untoward side effects.[16,17] In the Lancet editorial it is stated that, it is time (for medical doctors) to accommodate the possibility that many nutritional products may have valuable therapeutic effects and to regain the credibility of the public at large.[18] Further more in osteoarthritis, the joint capsule becomes thickened and the synovial fluid has a reduced concentration of lactate and glucose inhibiting the synthesis of hyaluronic acid (HA). NSAID is withdrawn to prevent its side effects (GIT, Renal, Hepatic)[30] Glucose amine sulfate relieves the symptoms of OA within 2 weeks and its effect persists al least up to 8 weeks.[28]

Conclusion

29. Rovati LC