Abstract

Genome Wide Association Study (GWAS) variants on chromosome 15q25 and 5p15 and genetic polymorphisms on the vascular endothelial growth factor (VEGF) gene showed that they may contribute to lung carcinogenesis. Therefore, this study was performed in order to assess the role of GWAS, and VEGF variants in non-small-cell lung cancer (NSCLC) prognosis.

Highlights

  • that they may contribute to lung carcinogenesis

  • this study was performed in order to assess the role of Genome Wide Association Study (GWAS)

  • Statistical significance was considered for p

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Summary

Open Access

The role of genetic polymorphisms at the chromosomes 5p15, 6p12, 6p21 and 15q25 in non-small-cell lung cancer prognosis: a Portuguese prospective study. Ramon A de Mello1,2*, Mónica Ferreira[3,4], Filipa S Pires[5], Sandra Costa[3,4], Michael Luis[2], João Cunha[6], Pedro Oliveira[7], Venceslau Hespanhol[1,5], Rui M Reis[3,4,8]. From São Paulo Advanced School of Comparative Oncology Águas de São Pedro, Brazil. From São Paulo Advanced School of Comparative Oncology Águas de São Pedro, Brazil. 30 September - 6 October 2012

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