Abstract

There is clear evidence in rodents that E2 enhances GC response to FSH. In vitro studies in non-human primates and women appear to suggest similar effects, although the influence of E2 on GC function has not been systematically tested in women, including those with PCOS. To determine this, we compared GC activity before and after FSH stimulation with or without an aromatase inhibitor (AI) during ovarian recovery from long-acting gonadotropin-releasing hormone agonist (GnRH agonist) leuproloide acetate.

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