Abstract
Background: Different technologies have been used in order to improve the endometrial condition as well as the quality of embryos; however, still the implantation process could fail. Endometrial Scratching (ES) has been proposed by many studies and revealed conflicting results. Objective: The study Aims to investigate the effect of ES on improving the Clinical Pregnancy Rate (CPR) and Live Birth Rate (LBR). Methodology: This is a retrospective study was carried out at Libyan National Fertility Centre. 188 Infertile women were included in the study in two different groups. 95 patients who underwent ES and 93 as control group. Cases with male factor infertility, history of surgical sterilization, premature ovarian failure, endometriosis and other hormonal disturbance (thyroid /prolactin) had been excluded from the study. Results: The CPR was positively affected by scratching procedure among infertile women after perform ES (p value 0.022). The secondary infertile patients have got significant benefit after performing ES by improving the CPR (P value 0.045). The ES has improved the CPR on patients with previous history of failed Intra-Cytoplasmic Semen Injection ICSI (P value 0.043). However, there was no statistically significant difference to the effect of ES on LBR. Conclusion: The study found that the ES has a positive role to improve the implantation among specific group of infertile couples. It is recommended to perform ES for couples with secondary infertility and previously failed ICSI cycle.
Highlights
IntroductionThe endometrial receptivity and quality of embryos are considered as important factors affecting the pregnancy rate
Different technologies of assisted reproductive conception have been used around world in order to improve the Clinical Pregnancy Rate (CPR) among infertile couples [1].The endometrial receptivity and quality of embryos are considered as important factors affecting the pregnancy rate
The study found that the Endometrial Scratching (ES) has a positive role to improve the implantation among specific group of infertile couples
Summary
The endometrial receptivity and quality of embryos are considered as important factors affecting the pregnancy rate. The structural anomalies in the uterine cavity such as congenital problems, fibroid, polyp, endometrial adhesion and endometrial thickness are major factors affecting the implantation and so the pregnancy rate [2, 3]. The development in diagnostic and therapeutic technology in order to improve the endometrial condition Scan and Hysteroscopy) as well as the quality of embryos, still the implantation of embryos could fail (35% of embryo transfer rate) [4,5]. Different technologies have been used in order to improve the endometrial condition as well as the quality of embryos; still the implantation process could fail. Has been proposed by many studies and revealed conflicting results
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