Abstract
Kidney transplantation is a life-saving procedure, which can improve the quality of life of patients with end-stage kidney disease . Although it is the most common transplantation surgery worldwide, it can lead to some serious complications. Nowadays, the most often used procedure to evaluate and diagnose complications like rejection of kidney graft is renal graft biopsy. Although it provides valid results, it remains an invasive procedure. For this reason, various biomarkers have been tested for graft evaluation, with donor derived cell free DNA (dd-cfDNA) being one of the most prominent ones. In this review of the literature, we summarise the different areas of application of this biomarker in kidney transplantation and we highlight its future potential.
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