Abstract

Multiple sclerosis (MS) is one of the autoimmune demyelinating diseases involved in the central nervous system (CNS) and its etiological factors believed to be both environmental and genetic factors . The disease affected brain and spinal cord with various characteristic involved defect of myelination , chronic inflammation , pathological effect on axon and oligodendrocyte . The herpesvirus family is play a vital role in pathogenicity of disease . Cytomegalovirus (CMV) from these family members which detected to have a role in MS and our results investigated a significant relation of CMV with MS between patients and controls . Besides a previous data which approved the effect of the level of vitamin D on MS development and modifications in patients . In this study the results achieve significant differences in the levels of vitamin D between the two groups under study .

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