Abstract

AbstractPurpose Development and evaluation of optimizing the ocular surface after two‐step LASIK, based on complianceMethods Assessed the ocular surface, tear film and tear production before and after optimization in patients after two‐step LASIK in 4 groups. Group 1 (A) ‐ high myopia and low degree of astigmatism ‐ (43), aged 18 to 35 years, group 2 (B) ‐ medium myopia and low degree of astigmatism – (32), aged 18 to 35 years, group 3 (C) ‐ myopia medium or high and medium degree of astigmatism – (37), older than 35 years, group 4 (D) ‐ hypermetropia medium or high and medium degree of astigmatism ‐ (32), older than 35 years. The criteria for preoperative drug correction of refractive surgery to the stage were the following diagnostic blocks: clinical data in diagnosis of dry eye and corneal status, corneal thickness, the definition of clinical refraction, including patient age, antioxidant and immune activity of tears, determine of complianceResults Pathogenetically substantiated the two preparations after two‐step LASIK ‐ moxifloxacin 0.5% and hydroxyproylguar and sorbitol in group A, and moxifloxacin 0.5% and hydroxyproylguar in group B provide medium compliance. Using only hydroxyproylguar and sorbitol in Group C and hydroxyproylguar in Group D demonstrated a high compliance.Conclusion First pathogenetically substantiated the choice of therapy based сompliance in patients after two‐step LASIK.

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