Abstract
BACKGROUND/OBJECTIVES: Methicillin-resistant Staphylococcus aureus (MRSA) is a serious nosocomial pathogen and colonized or infected patients are a major reservoir for patient-to-patient transmission. Despite strict adherence to infection prevention and control (IP&C) procedures, a general medicine unit serving nephrology, infectious disease and acute geriatric patients in our tertiary care teaching hospital continued to experience ongoing transmission and outbreaks of MRSA. The objective of the study was to determine the role that colonization pressure (CP) plays in nosocomial transmission of MRSA on a general medicine unit. Also, to propose a threshold CP above which additional IP&C practices should be implemented in order to prevent MRSA transmission and avoid an outbreak.
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