Abstract

In an experimental model system for kidney transplantation, the ability of the rat kidney to resynthesize ATP after warm ischemic time and subsequent restoration of renal blood flow was found to determine tissue viability and survival of the animal. The administration of CoQ 10 prior to warm ischemia enhanced the rate and extent of ATP resynthesis by reflow following two-hour warm ischemia and this was accompanied by an increase in survival rate of the rats.

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