Abstract
Purpose: Cushing’s disease is characterized by hypercortisolism due to excess secretion of adrenocorticotropic hormone (ACTH) from pituitary adenoma. Surgical resection of the tumor is the mainstay of management and pre-operative imaging of the pituitary tumor is important for optimizing surgical approach and minimizing complications. However, up to 40% of pituitary adenomas are not detected via standard T1-weighted MRI. Alternative methods include bilateral inferior petrosal sinus sampling (BIPSS) and contrast-enhanced MRI. However, BIPSS is invasive and technically challenging, and the use of contrast dye is contraindicated in patient populations such as those with kidney disease. The purpose of this study is to determine whether Constructive Interference in Steady State (CISS) sequence will be a beneficial adjunct to standard MRI protocol in Cushing’s disease patients.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
