Abstract
The role of Bleomycin in management of hypertrophic scars and keloids – A clinical trial
Highlights
Keloids and hypertrophic scars remain a nagging problem even with the emergence of multiple modalities in their treatment
The mechanism underlying keloid formation has not been fully defined though studies reveal that the activated fibroblasts and excessive collagen production are responsible for their occurrence
Keloids extend beyond the original wound, whereas hypertrophic scars tend to remain within the borders of the original wound [1]
Summary
Keloids and hypertrophic scars remain a nagging problem even with the emergence of multiple modalities in their treatment. Aims: The aim of this study was to define the role of Bleomycin and to confirm its effectiveness in the management o keloids and hypertrophic scars. Settings and Design: This was a prospective clinical trial involving 20 patients with hypertrophic scars and keloids. Conclusions: Bleomycin is one of the most effective and safest modality for the treatment of hypertrophic scars and keloids. Keloids and hypertrophic scars form due to uncontrolled dermoproliferation and are unique to humans. They occur following any kind of injury and lead to considerable cosmetic blemish. Keloids extend beyond the original wound, whereas hypertrophic scars tend to remain within the borders of the original wound [1]
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