Abstract
In previous studies, B cells were ignored in multiple sclerosis (MS)pathogenesis, and researchers have focused more on the role of T cells in this disease.Recent evidence shows that there is an antigen-driven B-cell response in the central nervous system of patients with multiple sclerosis, and memory B cells/plasma cells are detectable in MS lesions.Simultaneously, the breakthrough of B cell-depleting therapies indicates that B cells may affect the pathogenesis of MS than expected.However, the exact mechanism of B cells in MS remains unclear.This review summarizes the research and progress of B cells in the mechanism and clinical treatment of MS in the past few years, and briefly describes the role of B cells in the pathogenesis of multiple sclerosis. Key words: Multiple sclerosis; B cell; B cell-depleting therapy; Immune reaction
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
