Abstract
"Astrocytes are highly specialized glial cells and play a crucial role in neuronal functionality and brain functional integrity. Although research on Alzheimer’s disease has been concentrated mainly on the role of neurons, increasing evidence comes to light marking the important role of astrocytes in the pathophysiology of Alzheimer’s disease. Astrocytes undergo certain morphological changes in Alzheimer’s disease and they are thought to participate in Ab metabolism, and to mediate neurotoxicity and neuronal death through Calcium signaling. Here we briefly present the morphological changes of astrocytes and their role in Alzheimer’s disease neurodegeneration."
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