Abstract

The role of alginate-based therapy in gastroesophageal reflux disease

Highlights

  • The burden of the gastroesophageal reflux disease Gastroesophageal reflux disease (GERD) is one of the most common digestive pathologies, with worldwide spread and increasing incidence, consisting of all clinical symptoms, with or without lesions of the esophageal mucosa, caused by reflux of gastric contents into the esophagus [1]

  • The condition can present with extra-esophageal symptoms, including laryngitis, asthma, chronic cough and dental erosions [2,3]

  • The main complications that may occur in the evolution of GERD due to excessive exposure to gastric reflux are esophagitis, benign esophageal stenosis, esophageal ulcer, upper digestive hemorrhage, Barrett’s esophagus (EB) and the most unwanted complication, esophageal adenocarcinoma [11,12]

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Summary

General articles

Ana-Maria SINGEAP1,2, Laura HUIBAN1,2, Stefan CHIRIAC1,2, Tudor CUCIUREANU1,2, Anca TRIFAN1,2, FRCP. Popa” University of Medicine and Pharmacy, Iasi, Romania 2Institute of Gastroenterology and Hepatology, “St. Spiridon” Emergency Hospital, Iasi, Romania

INTRODUCTION
Clinical implications
Importance of treatment optimization
Pharmaceutical form Qualitative and quantitative composition per dose
Findings
CONCLUSIONS

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