Abstract
Gout is a common form of inflammatory arthritis where urate crystals deposit in joints and surrounding tissues. With the high prevalence of gout, the standardized and effective treatment of gout is very important, but the long-term treatment effect of gout is not satisfied because of the poor adherence in patients to the medicines. Recently, advanced imaging modalities, including ultrasonography (US), dual-energy computed tomography (DECT), and magnetic resonance imaging (MRI), attracted more and more attention for their role on gout as intuitive and non-invasive tools for early gout diagnosis and evaluation of therapeutic effect. This review summarized the role of US, DECT, and MRI in the management of gout from four perspectives: hyperuricemia, gout attacks, chronic gout, and gout complications described the scoring systems currently used to quantify disease severity and discussed the challenges and limitations of using these imaging tools to assess response to the gout treatment.
Highlights
Gout is a chronic disease of monosodium urate (MSU) crystal deposition and is one of the most common forms of inflammatory arthritis in adults, especially men
This review mainly focuses on the role of US, dual-energy computed tomography (DECT), and magnetic resonance imaging (MRI) in the management of gout
A study led by conventional CT, DECT, and XR techniques showed that urate crystals and soft tissue composition of tophi were directly associated with bone destruction scores, a significant reduction in soft tissue inflammation was associated with improved bone destruction after Urate-lowering therapy (ULT) [51]
Summary
Reviewed by: Yan Yang, University of Texas MD Anderson Cancer Center, United States Shaolin Shi, Nanjing University, China. Lin J (2022) The Role of Advanced Imaging in Gout Management. Gout is a common form of inflammatory arthritis where urate crystals deposit in joints and surrounding tissues. Advanced imaging modalities, including ultrasonography (US), dual-energy computed tomography (DECT), and magnetic resonance imaging (MRI), attracted more and more attention for their role on gout as intuitive and non-invasive tools for early gout diagnosis and evaluation of therapeutic effect. This review summarized the role of US, DECT, and MRI in the management of gout from four perspectives: hyperuricemia, gout attacks, chronic gout, and gout complications described the scoring systems currently used to quantify disease severity and discussed the challenges and limitations of using these imaging tools to assess response to the gout treatment
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