Abstract
1. 1. Renal responses of the lizard Dipsosaurus dorsalis to chronic administration of water, 50 mM NaCl and 150 mM NaCl were studied. 2. 2. D. dorsalis responded to these injections by reducing or increasing sodium excretion by means of appropriate variations in fractional reabsorption of sodium. 3. 3. Corticosteroidogenesis increased in response to saline loads but was unchanged with chronic water loading. 4. 4. Dexamethasone significantly inhibited the normal response to NaCl loading. 5. 5. Responses to aldosterone and spirolactone injections were negligible and suggest that aldosterone is not involved in the control of renal sodium excretion.
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