Abstract

1. 1. Acetate was the only substrate studied which was incorporated into fatty acids, and adipose tissue was the only tissue important in the biosynthesis of fatty acids. 2. 2. Glucose made only a minor contribution to respiratory CO 2, but it was quantitatively the most important substrate for the synthesis of triglyceride-glycerol in adipose tissue and intestinal mucosa. 3. 3. Substantial quantities of propionate were incorporated into 14CO 2, particularly in hepatic and mucosal tissue. 4. 4. In intestinal mucosa gluconeogenic pathways exist for the conversion of propionate to glyceride-glycerol. 5. 5. Glycerol kinase activity was detected only in bovine hepatic tissue.

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