Abstract
Background The cAMP response-element binding protein(CREB) is one of recently disclosed positive regulating factors of learning and memory. Recent evidences indicate that CREB may regulate learning and memory through multiple pathways. Objective To clarify the role and its relative mechanisms of CREB in regulating learning and memory, thus to provide insight in the preventive and therapeutic strategy for cognitive dysfunction diseases. Content The origination, structure, the role of CREB in regulating learning and memory and its mechanisms were discussed. Trend The exact upstream regulatory mechanism of CREB and its self-regulation need further studies. these studies on CREB might provide new targets and ideas for the prevention and treatment of cognitive disorder diseases. Key words: cAMP response-element binding protein; Learning and memory; Histone deacetylases; Cognitive dysfunction
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Anesthesiology and Resuscitation
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
