Abstract

Theresults ofthe Turku studies were soonrecognized, firstin the then-SovietUnion, wherexylitol hadbeenroutinely usedin the diets ofdiabetic subjects. Atwo-year study conducted inthe state ofKazakhstan demonstrated a >70%reduction in theoverall caries incidence in the xylitol group compared with thesucrose group. The next trials were those conducted under theauspices ofthe WorldHealth Organization. TwoWHOstudieswere successfully completed: one in French Polynesia (1981-84), andanotherin Hungary, intheearly 1980s. Theformertrialinvolved a 32-month

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