Abstract

In 1901, William Bateson, the biologist who coined the word genetics, presented his first “Report to the Evolution Committee of the Royal Society”. It included a footnote on “extraordinarily interesting” observations by Archibald Garrod, a physician at the Hospital for Sick Children in London: “Recently Garrod has noticed that no fewer than five families containing alkaptonuric members . . . are the offspring of first cousins . . . exactly the conditions most likely to enable a rare and usually recessive character to show itself.”

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