Abstract
The interrelation of the endocrine glands and the skin makes an apparent manifestation in a condition which the dermatologist is so frequently called on to treat, and which to my mind has not been coped with in an efficient manner, namely, acne. During adolescence the entire system is affected by the changes which are occasioned by the introduction into its life of an entirely new phase and character. The appearance of acne at the beginning of this unstable cycle of the life of the human being points strongly toward the veracity of my introductory statement that etiologically the basic factor may justly be looked for in a deranged endocrine mechanism, the poise of which suffers severely by the advent of a physiologic and biochemical change caused by the new processes which were ushered in by the active participitation of the gonads in body metabolism. ENDOCRINE IMBALANCE In the make-up of
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