Abstract
IntroductionThe aim of the study was to address the fatty acid (FA) status and its relationship with disease activity in patients with inflammatory bowel disease (IBD).MethodsFA levels of the phospholipid fraction in serum and a colon biopsy specimen were measured in 17 patients with IBD.ResultsA negative correlation between the histological activity of inflammation of the disease and the ratio of polyunsaturated FAs/no polyunsaturated FAs was observed. Moreover, the level of that ratio was lower in patients with IBDs as compared to controls.ConclusionsThe FA profile in serum and in a colon biopsy specimen in patients with IBD is characteristic for essential fatty acid insufficiency.
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