Abstract
The strophanthins, which we now know to be steroidal cardiac glycosides, were isolated from African plant sources (arrow poisons) in the late 19th century. By the 1880s, galenical preparations of strophanthus were commonly prescribed for cardiac patients as a substitute for digitalis. Intravenous (IV) strophanthin-K was popularised for the treatment of cardiac failure between 1910 and 1935. Experimental use of strophanthin-G (ouabain) in animals undergoing hypovolaemic shock in the 1940s prompted its IV use for the treatment of shock in man in the 1950s. Textbooks of anaesthesia recommended the strophanthins for resuscitation and treatment of shock until the 1970s, but by the 1980s, such use had waned.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
