Abstract

Proteins are small biological machines that work in our bodies as well as in the bodies of all animals, plants, viruses, and bacteria. They are responsible for a wide range of vital activities. Proteins are synthesized based on instructions contained in the genetic code, within their DNA, by a cellular organelle called ribosomes. The ribosome assembles proteins very quickly and accurately. Most of my scientific research is devoted to understanding the function of the ribosome, based on its structure, as we determined it. In this article, I describe the major findings of my research, some important applications of these findings, and the challenges I have faced along the way.

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