Abstract
The theory of multiple allelic genes accounting for the inheritance of the Rh reactions is well established. Fisher's hypothesis of eight genes, six pairs of allelic antigens, and six specific antibodies is the most comprehensive offered.The blood of 606 Canadians of Japanese race was tested with the four available antisera. Since this sample included entire families, gene analysis was based on a subsample of 217 unrelated individuals. The resulting analysis, based on Fisher's hypothesis, is given, and the probable reason for a discrepancy in the findings presented and further tested. Estimates of gene frequencies in per cent were as follows:[Formula: see text]These results are compared with previous studies on Japanese, and examined in relation to Fisher's hypothesis of three linked loci, and Fisher and Race's hypothesis of crossing over of elementary antigens.
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