Abstract
A prospective longitudinal study of the post-operative resensitisation of corneal transplants (penetrating keratoplasty)was carried out. The centre and periphery of the transplant was first assessed with the Cochet Bonnet aesthesiometer at 6 months after transplant, and then at regular intervals for at least 4 years (maximum 7 years). Individual resensitisation patterns varied greatly in the speed and extent of recovery. However, analysis of the data from all 66 subjects revealed a clear trend towards a slow, but progressive, centripetal resensitisation. At 4 years after transplant, 68% had no central sensitivity, while only 9% had normal sensitivity. By 7years after transplant, 39% were still without central sensitivity.
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