Abstract

To assess the possible role of plasmalogens in essential fatty acid deficiency, the metabolism of [6,8,9,11,12,14,15- 3H 7]arachidonic acid was examined in testicular tissue of rats maintained on essential fatty acid-deficient and control diets. The findings demonstrated that this essential fatty acid is metabolized more rapidly in the diacyl phospholipids and is retained to a greater extent in the plasmalogens of testicular lipids of the animals fed the essential fatty acid-deficient diet. It would appear that the build-up of labeled arachidonic acid in the plasmalogens from rats fed the fat-free diet is explained by an acyl exchange reaction, since the quantity of ethanolamine plasmalogens in the testes remained constant.

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