Abstract

Aim. To evaluate in-hospital and long-term results of surgical treatment of patients with infective endocarditis of the tricuspid valve, to compare the effectiveness of valve repair and valve replacement techniques, and to identify risk factors of mortality and reoperations. Materials and methods. 31 surgical patients with tricuspid valve infective endocarditis were evaluated. Patients were divided into 2 groups. In Group 1 (n = 14) repairs of the tricuspid valve were performed, in Group 2 (n = 17) patients had undergone tricuspid valve replacements. Epidemiological, clinical, microbiological and echocardiographic data were studied. Methods of comparative analysis, the Kaplan–Meier method, and Cox risk models were applied. Results. The most common complication of in-hospital stay was atrioventricular block (17.7% of cases in Group 2). In Group 1, this type of complication was not found. Hospital mortality was 7.14% in Group 1, and 0% in Group 2. Long-term results have shown the significant reduction of heart failure in general cohort and in both groups. In Group 1 the severity of heart failure in the long term was less than in Group 2. No significant differences in the severity of tricuspid regurgitation were found between the groups. In 7-year follow up no cases of death were registered in Group 1. Cumulative survival rate in Group 2 within 60 months was 67.3 ± 16.2%. No reoperations were performed in patients from Group 1. In Group 2, the freedom from reoperation within 60 months was 70.9 ± 15.3%. Combined intervention was found as predictor of postoperative mortality. Prosthetic valve endocarditis was identified as risk factor for reoperation. Conclusion. Valve repair and valve replacement techniques of surgical treatment of tricuspid valve endocarditis can provide satisfactory hospital and long-term results. Tricuspid valve repair techniques allowed reducing the incidence of postoperative atrioventricular block. In the long-term, patients after tricuspid valve repair have shown less severity of heart failure as well as better rates of survival and freedom from reoperation. Combined intervention and prosthetic endocarditis were found to be main risk factors for adverse outcome.

Highlights

  • No significant differences in the severity of tricuspid regurgitation were found between the groups

  • Для сравнения двух групп с несимметричным распределением использовали непараметрический критерий Уилкоксона–Манна–Уитни

  • Количество случаев с выявленными вегетациями на трикуспидального клапана (ТК) размером более 15 мм в группах представлено в табл

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Summary

ЭКСПЕРИМЕНТАЛЬНЫЕ И КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ

THE RESULTS OF SURGICAL TREATMENT OF TRICUSPID VALVE INFECTIVE ENDOCARDITIS USING VALVE REPAIR AND VALVE REPLACEMENT OPERATIONS. Aim. To evaluate in-hospital and long-term results of surgical treatment of patients with infective endocarditis of the tricuspid valve, to compare the effectiveness of valve repair and valve replacement techniques, and to identify risk factors of mortality and reoperations. In the long-term, patients after tricuspid valve repair have shown less severity of heart failure as well as better rates of survival and freedom from reoperation. Но если в хирургии ИЭ левых камер сердца уже к 80-м годам прошлого века была подтверждена необходимость и эффективтом XVII No 4–2015 ность ранних хирургических вмешательств на фоне активного инфекционного процесса, то в случаях ИЭТК выбор хирургического лечения на сегодня является более избирательным [19,20,21]. Цель исследования: оценить госпитальные и отдаленные результаты хирургического лечения пациентов с инфекционным эндокардитом трикуспидального клапана и сравнить эффективность клапаносохраняющих и клапанозамещающих методов при данной патологии, а также выявить факторы, влияющие на летальность и частоту реопераций

МАТЕРИАЛ И МЕТОДЫ
Крупные вегетации
При поступлении Перед выпиской Отдаленный
Функция свободы от реопераций
Full Text
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