Abstract
The article presents the results of the first observational study in the Russian Federation on the efficacy and safety of high doses of uridine monophosphate (150 mg) in combination with choline (the supplement neurouridine) in the treatment of patients with nonspecific low back pain. The Visual Analogue scale (VAS), the painDETECT questionnaire (PD-Q), the Roland-Morris Low Back Pain and Disability Questionnaire, the Hospital Anxiety and Depression Scale (HADS) and the Pittsburgh Sleep Quality Index were used to assess the efficacy of neurouridin in 50 patients with lower back pain. A conclusion was also made about a greater decrease in the intensity of pain in the main group than in the comparison group, a positive effect of treatment on a decrease in the severity of the neuropathic component of pain was not- ed according to the results of PD-Q, revealing signs of improved functional status according to the analysis of the Roland-Morris low back pain and disability questionnaire.
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