Abstract

Imagine you're a patient signing a consent form for an operation and only knowing about the good outcomes and none of the risks. This is akin to what is happening in much of science today. Negative studies don't get published and positive studies sometimes get published twice [1]. Such publication bias is skewing the research base to the detriment of scientific progress. There is strong evidence that much research remains unpublished and this is especially true of those studies with inconvenient or negative findings [2].

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