Abstract
First, we prepared the Poly-methyl-acrylic Acid hydrogels by free radical reaction, then prepared the Sodium-Poly-methyl-acrylic and Sodium-Alginate blend-micro-spheres by the condensation phase separation method. The influencing factors of the form and the particle size of the blend-micro-spheres were investigated including the content of the Sodium-Poly-methyl-acrylic, the content of the Sodium-Alginate, the content of the calcium chloride and the volume ratio for the Sodium-Poly-methyl-acrylic solution and the Sodium-Alginate solution. We also give a research on the swelling influencing factors of the blend-micro-spheres and observed its internal and external form by the scanning electron microscope (SEM) ; The result showed that: we can get the favorable appearance form blend-micro-spheres when the Content of PMAA 4.0%，the Content of SA 4.0%，the Content of CaCl2 4.0%; and it had a important means when the volume ratio for the Sodium-Poly-methyl-acrylic solution and the Sodium-Alginate solution was 1:4 , 1:1.
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