Abstract

Objective To investigate the value of color-coded digital subtraction angiography (iFlow) in the study of normal cerebral hemodynamic parameters, so as to set up parameter for normal cerebral hemodynamic. Methods From march 2013 to september 2016, We retrospectively analyze a total of 60 patients in wuhan general hospital of PLA. These patients were reexamined with digital subtraction angiography (DSA) due to follow-up for postembolization with aneurysms by naked coins, and were suspected as intracranial vascular diseases with normal angiography findings in DSA. In order to measure the time to peak (TTP) of contrast medium in region of interest (ROI). we set the ROI at these rigion: ROI-1: internal carotid artery bifurcation; ROI-2: cerebral middle artery bifurcation; ROI-3: the middle of superior sagittal sinus; ROI-4: torcular herophili area; ROI-5: the end of basilar artery. Results The TTPs of ROI-1 to ROI-4 in left internal carotid artery angiography and ROI-5 in left vertebral artery angiography are (2.70±0.37), (2.85±0.36), (7.98±1.54), (8.85±1.77), (3.02±0.58) s respectively. The TTPs of ROI-1 to ROI-4 in right internal carotid artery and ROI-5 in right vetebral artery angiography are (2.77±0.35), (2.87±0.36), (8.01±1.14), (8.77±1.26), (3.06±0.55) s respectively. Conclusion The technique of iFlow provides a reference value index in normal cerebral hemodynamic, and set up a noval method in the research of cerebral hemodynamic. Key words: Color-coded digital subtraction angiography; Cerebral perfusion; Hemodynamic; Time to peak

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