Abstract

PurposeTo rebuild the three-dimensional (3-D) model of the anterior segment by high-speed swept-source optical coherence tomography (SSOCT) and evaluate the repeatability of measurement for the parameters of capsule-intraocular lens (C-IOL) complex.MethodsTwenty-two pseudophakic eyes from 22 patients were enrolled. Three continuous SSOCT measurements were performed in all eyes and the tomograms obtained were used for 3-D reconstruction. The output data were used to evaluate the measurement repeatability. The parameters included postoperative aqueous depth (PAD), the area and diameter of the anterior capsule opening (Area and D), IOL tilt (IOL-T), horizontal, vertical, and space decentration of the IOL, anterior capsule opening, and IOL-anterior capsule opening.ResultsPAD, IOL-T, Area, D, and all decentration measurements showed high repeatability. Repeated measure analysis showed there was no statistically significant difference among the three continuous measurements (all P > .05). Pearson correlation analysis showed high correlation between each pair of them (all r >0.90, P<0.001). ICCs were all more than 0.9 for all parameters. The 95% LoAs of all parameters were narrow for comparison of three measurements, which showed high repeatability for three measurements.ConclusionSSOCT is available to be a new method for the 3-D measurement of C-IOL complex after cataract surgery. This method presented high repeatability in measuring the parameters of the C-IOL complex.

Highlights

  • A significant interaction between the capsular bag and the intraocular lens (IOL) is maintained for a long time after cataract surgery.[1, 2] Any change of the capsule-IOL (C-IOL) complex can have important consequences on the postoperative IOL stability and subsequent refraction,[1, 3] and posterior capsule opacity (PCO).[2, 4,5,6,7] Thanks to the technological advances of IOL designs and IOL power calculation, cataract surgery can be considered a refractive procedure.[8]

  • sweptsource optical coherence tomography (SSOCT) is available to be a new method for the 3-D measurement of C-IOL complex after cataract surgery

  • The precise measurement and objective evaluation of the C-IOL complex might provide the basis for IOL design improvement, which may lead to better clinical outcomes in the future

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Summary

Introduction

A significant interaction between the capsular bag and the intraocular lens (IOL) is maintained for a long time after cataract surgery.[1, 2] Any change of the capsule-IOL (C-IOL) complex can have important consequences on the postoperative IOL stability and subsequent refraction,[1, 3] and posterior capsule opacity (PCO).[2, 4,5,6,7] Thanks to the technological advances of IOL designs and IOL power calculation, cataract surgery can be considered a refractive procedure.[8] premium IOLs, including aspherical, toric, and multifocal IOLs, are more sensitive to the position in the capsule bag. Previous studies have focused on the C-IOL complex in vivo using different devices, including slitlamp,[2] Scheimpflug videophotography (EAS-1000), [1] and optical coherence tomography (OCT).[9,10,11]

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