Abstract
Introduction: The treatment of choice for ACTH-producing pituitary adenomas is complete removal using a transsphenoidal approach. However, even after gross total removal, high levels of ACTH and cortisol can be occasionally found in the first postoperative days. These hormonal findings could lead to a misdiagnosis of surgical failure with a later cortisol and ACTH drop. We propose an evaluation of intraoperative plasma ACTH and its correlation to hormonal postoperative findings to help improve the prediction of surgical success in patients with ACTH-producing adenomas.
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