Abstract
AbstractRelative sensitivity and correlations between the Microtox® test and three commonly used acute lethality bioassays (i.e., rainbow trout, fathead minnow, Daphnia) are reviewed and discussed. All relevant data available for comparison were separated and evaluated based on chemical groupings. Generally, Microtox was more sensitive than or as sensitive as the acute lethality tests for pure individual organics, but was less sensitive to most inorganics. Microtox was not as sensitive as acute lethality tests to effluents or leachates with a high component of insecticides, herbicides, inorganics, pharmaceuticals or textiles, or highly lipophilic contaminants. As the complexity and toxicity of industrial effluents increased, the correlations and sensitivity of Microtox increased, with a corresponding decrease in data variability. Additionally, limitations of the available data are that (1) comparisons of relative sensitivity varied with the compounds and organisms tested; (2) there was a lack of standardization in approach and a failure to provide adequate details on the origin of the cited toxicity data, which confused and obscured comparisons; and (3) published reviews commonly failed to identify fish species and test details for cited data.
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