Abstract
Free-radical phenylation of isoquinoline has been effected both by photolysis of phenylthallium(III) di(trifluoroacetate) and by the action of pentyl nitrite on aniline. Analysis of the isomeric phenyl isoquinoline mixture by g.l.c. and h.p.l.c. established the reactivity order in the isoquinoline nucleus to be 1 > 5 > 8 > 4 > 3,6,7. This experimental order is compared with the eight published theoretical predictions, none of which is correct.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
