The Relative Contributions of Chlorogenic Acid and Rutin to Antioxidant Activities of Two EndemicPrangos(Umbelliferae) Species (P. HeyniaandP. Denticulata)

Abstract

The aim of this study was to investigate the metal chelating, radical-scavenging and anti-lipid peroxidative properties and the chlorogenic acid/rutin contents of two endemic Prangos species; Prangos heyniae H. Duman & M. F. Watson and Prangos denticulata Fisch. & Mey. According to high-performance liquid chromatography analysis, the highest rutin and chlorogenic acid contents were found in P. denticulata leaf methanol extract (33.6 ± 2.8 μg/mg extract) and P. heyniae leaf methanol extract (24.8 ± 0.2 μg/mg extract), respectively. The water and methanol extracts of the species showed high scavenging abilities and significant capacities to suppress lipid peroxidation. These results demonstrated that chlorogenic acid may be an important component in the antioxidant activities of these Prangos species. Practical Applications Prangos Lindl. (Umbelliferae) species are known as “Çakşir otu” in Turkey and used to make herbed cheese to give the desired aroma and taste. Young shoots of Prangos species are used as boiled vegetables and pickles. Prangos species have been used in folk medicine as emulient, carminative, to stop bleeding and heal the scars. The results demonstrated that the extracts of two Prangos species exhibited good antioxidant activity, which correlated with high polyphenol content. Therefore, they may be used as a potential source of natural antioxidants for food supplementation or development of nutraceuticals.