Abstract
L-Tryptophan (L-Trp), the sum of five competing amino-acids (CAA) — i.e. valine, leucine, isoleucine, tyrosine, phenylalanine — Cortisol and adrenocorticotropic hormone (ACTH) were determined both before and after treatment with 1 mg dexamethasone in 24 females 3 days after childbirth. Basal L-Trp concentrations were significantly lower in postpartum females as compared to normative values. There was a significant suppressing effect for dexamethasone on the availability of L-Trp. Up to 75% of all females showed Cortisol non-suppression (postdexamethasone Cortisol ≥5 μg/dl). The baseline Cortisol and ACTH levels were significantly positively related to the availability of L-Trp. We found a positive relationship between basal L-Trp values and the post dexamethasone ACTH values.
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