Abstract
1. 1. When 106 patients with carcinoma of the oral cavity, pharynx or larynx were interviewed concerning their use of alcoholic beverages and tobacco, 92 per cent reported that they drank significant amounts of alcohol daily. A history of heavy consumption of alcohol was given by 62 per cent of the patients, and 85 per cent smoked the equivalent of one or more packs of cigarettes a day. 2. 2. Of the 106 patients interviewed, eightynine were men and seventeen were women, a ratio of 5.2:1. The median age of diagnosis for the entire series was sixty-two years. 3. 3. Of all of the patients with oral carcinoma in this study, a second primary malignant lesion developed in 7.5 per cent. 4. 4. Additional supporting evidence is presented that the habitual use of tobacco and alcohol plays an important role in the cause of oral carcinoma. The etiologic mechanism is not understood, but possible related factors are discussed.
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