The Relationship of Health-Related and Health-System Factors with Patient-Centered Communication, HPV-Related Knowledge, and Perceived Effectiveness of the HPV Vaccine

Abstract

ABSTRACT Background HPV is associated with several cancers, yet HPV vaccine uptake rates remain suboptimal. Enhancing HPV vaccine promotion requires looking beyond individual characteristics and conducting a thorough evaluation of how health-related and health system factors may influence HPV vaccine uptake. Purpose Our study explores the relationship of health-related and health-system factors with patient-centered communication, HPV-related knowledge, and perceived effectiveness of the HPV vaccine. Methods We used data from HINTS 5, Cycle 1, and performed structural equation modeling to explore the impact of health-related and health system factors on perceived HPV vaccine effectiveness, both directly and via HPV knowledge and patient-centered communication. The predictors in our model included health-related factors and health-system factors. Results Findings suggest a direct relationship between HPV knowledge and perceived vaccine effectiveness (β = 0.73; p < .05), and patient-centered communication and perceived vaccine effectiveness (β = 0.07; p < .05). Frequency of doctor visits directly and negatively predicted patient-centered communication (β = -0.04, p < .05). Self-reported health status was directly and positively related to HPV vaccine acceptability (β = 0.147, p < .05). Having a chronic condition (β = -0.09, p =< 0.05) and depression/anxiety (β = 0.141, p < .05) was related to HPV vaccine acceptability, via knowledge. Discussion These findings enhance our nuanced understanding of the intricate interplay between health-related and health-system factors in shaping perceptions and attitudes toward HPV vaccination. Translation to Health Education Practice Accounting for health-related and health system factors is essential for effective dissemination of HPV information.