Abstract

The relationship of gray zone and infarct core in the Iceland MI study

Highlights

  • Gray zone or infarct heterogeneity, defined as the admixture of necrotic and viable myocardium at the periphery of myocardial infarction (MI), has been noted to be a modulator of cardiac outcomes

  • We report the data from 215 individuals who were found to have myocardial infarction by late gadolinium enhancement on CMR

  • When gray zone was normalized to total scar size, it had a negative correlation with infarct core, rho of -0.53 (-0.62–0.42), P < 0.0001

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Summary

Background

Gray zone or infarct heterogeneity, defined as the admixture of necrotic and viable myocardium at the periphery of myocardial infarction (MI), has been noted to be a modulator of cardiac outcomes. Most studies have not reported a direct correlation between infarct core and the zone of heterogeneity. No large population based studies have examined the burden of undiagnosed infarct and infarct heterogeneity

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