The relationship of fasting glucose in basic state with the results of head-up tilt table test in children

Abstract

Objective To explore the relationship of fasting glucose in basic state with the results of head-up tilt table test (HUTT) in children.Methods We choosed 157 cases of children (male 86 and female 71) with unexplained syncope,headache,dizziness and sigh,they were 3 ～ 18 (11.34 ± 3.29) years old and were outpatients or had been hospitalized in the Second Xiangya Hospital of Central South University from Sep 2012 to Feb 2013.The HUTT were carried on after eliminate organic disease of heart,head,bloodvessel and other reasons caused by the above symptoms and obtain written informed consent from participants or guardian.Before HUTI,trace fasting glucose of children would be monitored in based condition.Results (1) Between HUTT negative group (n =63) and HUTT positive group (n =94),there was no significant difference in fasting glucose [(5.40 ± 0.52) mmol/L vs (5.35 ± 0.61) mmoL/L,t =-0.590,P ＞ 0.05].(2) Only 1 case of heart inhibited type vasovagal syncope did not be included in 94 children with HUTT positive.There were no significant differences in fasting glucose between vascular inhibited type vasovagal syncope (n =67) and mixed vasovagal syncope (n =10) and orthostatic tachycardia syndrome (n =16)[(5.34 ±0.54) mmol/L vs (5.07 ±0.64) mmol/L vs (5.49 ±0.81) mmol/L,P ＞0.05].(3) Among 67 cases of vascular inhibitory type vasovagal syncope in children,two kinds induced way of based tilt table test (n =16) and sublingual nitroglycerin tilt table test (n =51) showed no significant differences in fasting glucose [(5.32 ±0.54) mmol/L vs (5.35 ±0.55) mmol/L,t =0.166,P ＞0.05].(4) In two groups of fasting glucose ＜5.5 mmol/L and ≥5.5 mmol/L,HUTT negative rate [37.63％ (35/93) vs 43.75％ (28/64)] and HUTT positive rate [62.37％ (58/93) vs 56.25％ (36/64)] showed no statistical significance (x2 =0.585,P ＞ 0.05).Conclusion Fasting glucose in basic state has no predictive value to HUTT results in children. Key words: Fasting glucose; Head-up tilt table test; Children