The relationship of endocrine and gastroenterological pathology: dietary fiber as a mechanism of management

Abstract

Gastroenterological manifestations of endocrine diseases are an additional factor that reduces the quality of life of patients. In some cases, gastroenterological symptoms are the reason for the patient’s coming to the doctor and the detection of endocrine disease. The pathogenetic aspects of the development of disorders of the gastrointestinal tract are diverse, and therefore, unfortunately, it is not always possible to eliminate gastroenterological symptoms by only compensating the underlying disease. The combination of pathology of the gastrointestinal tract and the endocrine system can mutually aggravate the course of each other. There are also cases when gastroenterological pathology can be the root cause of some metabolic diseases, in particular, malabsorption. Currently, the possibilities of correction of gastroenterological pathology are widely studied in order to achieve compensation for the patient’s endocrine pathology, as well as to improve the quality of life of patients. The main directions are measures aimed at restoring the passage of food contents, maintaining the integrity of the intestinal wall, eliminating the inflammatory factor, as well as restoring the gu microbiota (GM) and modulating its metabolism. The latter method of correcting violations seems to be the most promising today due to the constantly growing number of scientific publications, as well as a wide range of safe and effective ways to influence GM. In addition to dietary recommendations, the issue of prescribing dietary fiber (DF) to patients as a food substrate for GM and a mechanism for controlling the number and ratio of microorganisms is becoming increasingly relevant.