Abstract
Abstract. In a group of 8 midtrimester pregnant patients, the uterine volume (V) had been increased by the intra‐amniotic instillation of 350 ml Macrodex and the changes in plasma progesterone (P) and intrauterine pressure (IUP) had been measured. In 2 of these 8 women the study was discontinued because of the early rupture of the fetal membranes. In 4 patients the P levels decreased slightly and IUP increased, culminating in abortion. In 2 patients the P levels increased distinctly, the IUP remained unchanged and pregnancy continued undisturbed. These findings support Csapo's conclusion that the ratio V/P controls IUP and thus the fate of pregnancy.
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