Abstract
Cardiovascular disorders are refer to the class of diseases that involve the heart or blood vessels (arteries and veins). While the term technically refers to any disease that affects the cardiovascular system. Cholesterol is classified as a sterol (a contraction of steroid and alcohol).Although cholesterol is essential for life; high levels in circulation are associated with atherosclerosis. Triglyceride (more properly known as triacylglycerol , TAG or triacylglyceride) is a glyceride in which the glycerol is esterified with three fatty acids. It is the main constituent of vegetable oil and animal fats.High-density lipoproteins (HDL) is one of the 5 major groups of lipoproteins (chylomicrons, VLDL, IDL, LDL, HDL) which enable lipids like cholesterol and triglycerides to be transported in the blood stream. In healthy individuals, about thirty percent of blood cholesterol is carried by HDL. Uric acid (or urate) is non-protein nitrogen compound with the formula C5H4N4O3. This study aimed to determine the relation between uric acid, cholesterol, triglyceride and HDL-cholesterol concentration in cardiovascular disorders patients. Serum sample were collected from 84 cardiovascular disorders patients attended to the general hospital of Alnasseriya. All samples were analyzed for uric acid , cholesterol, triglyceride and HDL-cholesterol concentration by enzymatic-colorimetric method kits. The data showed a highly significant increased in the serum concentration of uric acid , cholesterol and triglyceride in cardiovascular disorders patients compared with healthy control (P<0.01) .In addition , there was no significant increased in the serum concentration of HDL-cholesterol in cardiovascular disorders patients compared with healthy control (P>0.05) .The data of this study strengthen the possibility that high concentration of uric acid may act as a risk factor in cardiovascular disease.
 Key words: high density lipoprotein (HDL-cholesterol),very low density lipoprotein(VLDL), low density lipoprotein(LDL),intermittent lipoprotein(IDL), hyperuricemia.
Highlights
Cardiovascular disorders is any disorder that affects the heart's ability to function normally[1]
Data illustrated by table [3] clearly shows a highly significant increased (P0.05) in between the mean concentration of HDLcholesterol in patients and healthy control .In addition, the study shows a highly significant increased (P
This study showed the concentration of cholesterol and triglyceride was highly elevated in cardiovascular disorders patients compared with the healthy control groups
Summary
Cardiovascular disorders is any disorder that affects the heart's ability to function normally[1]. Cholesterol is a waxy material that is found in many food items including milk, cheese ,eggs, butter ,fish, beet, pork, chicken, goat meat, it is naturally occurring, fat-like substance with a complex chemical formula, and is used to build cells and make hormones.Itis present in plasma mainly esterified with fatty acids. Triglycerides are composed of fatty acid molecules and are the basic chemicals contained in fats in both animals and plants[4]. (Referred to as the "good" cholesterol) It is formed in the liver and walls of the small intestine, while maturing in blood stream, it obtains cholesterol from the surrounding tissues.The blood circulation transports the HDL back to the liver , from where the cholesterol is excreted in the bile[5]. The normal limits of serum uric acid are between 387 and 416 μmol/L in men and lower than 327 μmol/L in women[6].Hyperuricemia is usually defined as a serum uric acid level of 416 μmol/L or higher in men, and 357 μmol/L or higher in women[7,8]
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