The Relationship Between Total Lymphocyte Count and Viral Load Examination Results in HIV on Arv Patients at UPTD Puskesmas Putri Ayu Jambi City

Abstract

Background: Human Immunodeficiency Virus (HIV) infection causes destruction of the body's immune system in humans, causing AIDS (Acquired Immunodeficiency Syndrome). The total number of lymphocytes is one of the parameters used as an initial screening to assess the cellular immune response in people with HIV. One of the causes of the decrease in the total number of lymphocytes is the presence of the effect of taking antiretrovirals (ARVs)
 Method: The research design is quantitative research with a cross sectional approach. The data in this study used 39 samples of HIV patients who received ARV therapy for more than 6 months in the form of the total number of lymphocytes and viral load at the Putri Ayu Health Center. Patients with HIV were selected according to inclusion and exclusion criteria and then the data were analyzed univariately and bivariately with chi-square tests.
 Result: Most respondents had a normal total lymphocyte count of 26 people (66.7%) and most respondents had an undetectable viral load of 26 people (66.7%). Based on the Statistical Test Results, a p-value of 0.000 (p, <0.005) was obtained. These results show that there is a significant relationship between the total lymphocyte count and the results of viral load examination.
 Conclusion: there is a relationship between the total number of lymphocytes and viral load in HIV patients who received ARV therapy at Putri Ayu Health Center.