Abstract

The relationship between the percentage saturation of maternal and cord plasma transferrin and the maternal and cord blood free erythrocyte protoporphyrin:haem ratio were investigated in 49 healthy mothers following an uncomplicated pregnancy, and in their full term newborn infants. The variables studied were plasma iron, plasma total iron-binding capacity, percentage saturation of plasma transferrin, free erythrocyte protoporphyrin:haem ratio and haematocrit value. The same variables were also investigated in a group of 60 healthy university students. Though the measurement of free erythrocyte protoporphyrin:haem ratio has broad application in public health studies, little information is available regarding the possible application and clinical use of this variable in the Nigerian population. The results obtained suggest that the free erythrocyte protoporphyrin:haem ratio of blood has a significant negative correlation with that of the percentage saturation of plasma transferrin of the sample. The maternal percentage saturation of plasma transferrin has a significant positive correlation with that of the corresponding fetal (cord) sample. There was no significant correlation between maternal and cord free erythrocyte protoporphyrin [FEP]:haem ratio.

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