Abstract
Objective To analyze the effect of craniotomy area on the development of normal pressure hydrocephalus after decompressive craniotomy. Methods The clinical data of 34 patients with traumatic brain injury who underwent unilateral craniotomy from January 2012 to April 2018 at Department of Neurosurgery, Tangdu Hospital, Airforce Military Medical University were retrospectively analyzed. The effects of multiple factors on hydrocephalus, including the gender, age, Glasgow coma scale before craniotomy, open injury, extent of midline shift on CT before craniectomy, duration of operation, intracranial pressure after craniotomy, cerebrospinal fluid infection and craniotomy area were analyzed. Results Univariate analysis showed that the age (P=0.016), preoperative Glasgow coma scale (P=0.018), craniotomy area (P 0.05). It was also suggested by multiple logistic regression that craniotomy area (OR=1.138, 95% CI: 1.005-1.288, P=0.042) was an independent risk factor for hydrocephalus. Conclusion After decompressive craniotomy, the skull defect area may increase the risk of hydrocephalus. Key words: Craniocerebral trauma; Hydrocephalus, normal pressure; Decompressive craniectomy; Area size of craniectomy; Cerebrospinal fluid dynamics
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