The relationship between symptomatic status and aneurysm wall enhancement characteristics of single unruptured intracranial aneurysm.

Abstract

We aimed to analyze the aneurysm wall enhancement (AWE) characteristics of asingle unruptured intracranial aneurysm (UIA) and observe the relationship between the symptoms of asingle UIA and the aneurysm wall. In our hospital, 85patients diagnosed with asingle UIA using computed tomography angiography (CTA) were retrospectively analyzed. The patients were divided into symptomatic and asymptomatic groups, including 46asymptomatic and 39symptomatic aneurysms. High-resolution magnetic resonance imaging of the vascular wall (HR-MR-VWI) was utilized to ascertain the presence, degree, and extent of AWE and thick-wall enhancement. In addition to AWE characteristics, morphological parameters of aneurysms, such as maximal size, shape, height, neck width, aspect ratio (AR), and size ratio (SR), were scanned using CTA. The differences in the parameters of asingle UIA between the two groups were compared. An investigation explored the correlation between the symptom status of asingle UIA and AWE. We observed acorrelation between symptom status and maximal size, height, and neck width for asingle UIA, the presence or absence of AWE, and the levels and boundaries of AWE and thick-wall reinforcement. This study found that the AWE range was independently correlated with symptom status in the multivariate regression analysis. Alarger AWE range was an independent risk factor for the onset of symptoms in asingle UIA.