The relationship between stressful life events and the error-related negativity in children and adolescents

Abstract

The error-related negativity (ERN) has been cited as a neural marker that indexes risk for anxiety in children and across development. Environmental factors, such as punishment in the lab and parenting styles, have been shown to impact the ERN. However, little is known about how other environmental factors may shape this neural risk marker. The current study examines how the environmental factor of stressful life events may relate to the ERN in children and adolescents. In a sample of 176 females, ages 8–15 years, we examined associations between the frequency of recent stressful life events and the ERN. We also investigated whether interpersonal dependent life events or non-interpersonal life events uniquely relate to the ERN. Finally, we explored whether recent stressors differentially relate to the ERN based on age. Results suggest that youth who have experienced more frequent stressful life events have an increased (i.e., more negative) ERN. Moreover, more frequent interpersonal dependent stressors uniquely predicted the magnitude of the ERN. Lastly, results supported a moderation model wherein the relationship between the frequency of interpersonal dependent stressors and the ERN was moderated by age, such that the relationship between stressors and the ERN was significant only for younger children.